I Am Legend 2 (2025) picks up years after the events of the first film. Will Smith’s character, Robert Neville, is revealed to have perished, and the plot shifts to focus on his daughter, Marley (played by a new lead, perhaps a fresh face in Hollywood). The sequel explores the aftermath of the virus, with society still struggling to rebuild and the mutated “Darkseekers” still a constant threat.

Marley, now an adult, uncovers a breakthrough that could potentially reverse the virus. However, the infected are evolving, developing heightened intelligence, and they begin to organize. A dangerous conflict emerges as Marley attempts to lead a group of survivors to a safe haven. The film features a shocking twist when it’s revealed that Neville’s research was never truly completed, and Marley must take it a step further — ultimately making the ultimate sacrifice to ensure humanity’s survival.